Which of the following effects of climate changes poses the greatest threat to the Pacific region?

1. Rising sea levels

2. Increased frequency and intensity of natural disasters
3. Coral bleaching and destruction of marine ecosystems

Among these options, rising sea levels pose the greatest threat to the Pacific region. This is because many small island nations in the Pacific are low-lying and vulnerable to inundation from rising sea levels. This can lead to loss of land, displacement of populations, and increased risk of flooding and erosion.