What would happen to a cell that lacked smooth endoplasmic reticulum?

It would not be able to make lipids

It would not be able to replicate DNA

It would not be able to produce tRNA.

Its cell membrane would be impermeable.

The cell would not be able to synthesize lipids and detoxify substances, as smooth endoplasmic reticulum plays a crucial role in these functions. This could affect the cell's ability to maintain its structure and function properly.