Which of the following was one major effect on the bubonic plague

The bubonic plague had several major effects, but one of the most significant was the significant loss of population. It is estimated that around 25 million people, or roughly one-third of Europe's population, died because of the plague. This massive loss of life had profound social, economic, and cultural consequences, impacting feudalism, labor shortages, and even the art and literature of the time.

It killed nearly 1/3 of the population of Europe

It drove many poor people from cities in to manors it strengthen the power of the church
It led to that explosion of Muslims and Jews from Spain

The first statement is correct - the bubonic plague, also known as the Black Death, killed nearly one-third of Europe's population.

However, the second statement is not entirely accurate. While the plague did cause some people to flee from affected cities, it did not necessarily drive them into manors specifically. Instead, many people fled to rural areas to escape the infected cities. Additionally, it is worth noting that the plague affected people of all social classes, not just the poor.

The third statement is not directly related to the bubonic plague. While there were certainly instances of discrimination and persecution against minority groups during the time of the plague, the expulsion of Muslims and Jews from Spain was a separate historical event known as the Spanish Inquisition, which occurred several centuries later.