What will be the outcome of deletion of the third base, A from the DNA sequence below? Assume that the first base corresponds to the start of a codon.
C C A A A T A A A G
If the third base, A, is deleted from the DNA sequence "C C A A A T A A A G," the resulting sequence would be "C C A A T A A A G."
This deletion would cause a shift in the reading frame during translation. Each codon in the DNA sequence is composed of three bases, and the reading frame determines how these codons are grouped into amino acids during translation.
Deleting the third base (A) would disrupt the normal grouping of codons into triplets, resulting in a different amino acid sequence being produced during translation. This shift in the reading frame can have significant effects on the resulting protein, potentially leading to a completely different protein being synthesized or a non-functional protein.