Which of the following best describes how the Spanish and Hernando de soda impacted the native Americans living in the south eastern region of North America? A. Native Americans benefited from learning about new technologies from the Europeans.B. They formed a strong alliance and became trading partners.C. The Native Americans were introduced to new foods.D. Thousands of native Americans died as a result of diseases spread contact with Europeans.

D. Thousands of native Americans died as a result of diseases spread contact with Europeans.