One major consequence of Spanish conquests in the Americas was the decimation of native populations. The arrival of the Spanish led to the spread of diseases, such as smallpox, for which the native populations had no immunity. This resulted in significant loss of life, estimated to be in the millions. Additionally, the Spanish enslaved and exploited the indigenous people, leading to further depopulation and cultural devastation. The conquests also led to the seizure of land and resources, allowing Spain to establish an extensive colonial empire in the Americas.
