Which of the following statements are true with regard to recombinant DNA? (Select correct two responses)

1. Recombinant DNA is formed by combining pieces of DNA from different sources.

2. Recombinant DNA technology is used in genetic engineering and biotechnology.
3. Recombinant DNA can only be formed in bacteria.
4. Recombinant DNA can be used to produce genetically modified organisms (GMOs).
5. Recombinant DNA can only be used in medical research.