Holly wants to make a frame for painting. The painting is square and has an area of 225 square inches. The framing material costs $1.35 per inch. How much will Holly spend framing the picture?

Since the painting is square, each side is √225 = <<15=15>>15 inches.

Since the painting is square, the frame will also be square which means it will also be 15 inches on each side.
The area of the frame is (15+2*1.35)(15+2*1.35) = (15+2.7)(15+2.7) = 14.7*14.7 = <<14.7*14.7=216.09>>216.09 square inches.
Holly will therefore spend 1.35*216.09 = <<1.35*216.09=291.4285>>291.4285 dollars framing the picture. Answer: \boxed{291.43}.

To calculate the cost of framing the picture, we need to find the perimeter of the square painting. Since the painting is square, each side of the painting will be √(225) = 15 inches.

The perimeter is calculated by multiplying the length of one side by 4: 15 inches × 4 = 60 inches.
Now, we need to multiply the perimeter by the cost of the framing material: 60 inches × $1.35 = $<<60*1.35=81>>81.
Therefore, Holly will spend $81 framing the picture.

To find out how much Holly will spend framing the picture, we need to calculate the perimeter of the square painting and then multiply it by the cost per inch for the framing material.

First, let's find the side length of the square painting by taking the square root of its area. The area is given as 225 square inches, so the side length would be the square root of 225, which is 15 inches.

Since the painting is square, all four sides are equal in length. Therefore, the perimeter of the painting is 4 times the side length, which is 4 * 15 = 60 inches.

Now, multiply the perimeter of the painting (60 inches) by the cost per inch for the framing material ($1.35 per inch) to get the total cost of framing.

60 inches * $1.35/inch = $<<60*1.35=81>>81.

Therefore, Holly will spend $81 framing the picture.