Which factors were MOST responsible for the population decline among South American Indians after the Spanish conquest? Choose the TWO best answers.

A. forced labor in silver mines and on plantations
B. warfare between the Spanish and South American Indians
C. diseases introduced by the Spanish
D. famine caused by the disruption of traditional agriculture

The two best answers are C. diseases introduced by the Spanish and D. famine caused by the disruption of traditional agriculture.

The two factors that were most responsible for the population decline among South American Indians after the Spanish conquest are:

C. Diseases introduced by the Spanish
D. Famine caused by the disruption of traditional agriculture

To identify the TWO best answers for the factors responsible for the population decline among South American Indians after the Spanish conquest, we can examine the historical records and literature on the topic. Here is how you can find the answer:

1. Start by researching the historical context of the Spanish conquest of South America, particularly focusing on the impact on the indigenous population.

2. Look for reputable sources such as books, academic articles, or scholarly journals that discuss the consequences of the Spanish conquest on South American Indians.

3. Read about the different factors that contributed to the population decline, such as forced labor, warfare, diseases, and famine, among others.

4. Assess the impact and significance of each factor to determine which were the most responsible for the decline.

Based on historical research, the TWO best answers for the factors most responsible for the population decline among South American Indians after the Spanish conquest are:

A. Forced labor in silver mines and on plantations: The Spanish colonial authorities imposed brutal working conditions on indigenous people, compelling them to work in harsh environments such as silver mines and plantations, resulting in high mortality rates.

C. Diseases introduced by the Spanish: The arrival of the Spanish also brought diseases, such as smallpox, measles, and influenza, for which the South American Indians had no immunity. The introduction of these diseases led to widespread epidemics that decimated the indigenous population.

While warfare (B) and famine caused by the disruption of traditional agriculture (D) were also contributing factors, they were not as significant in terms of sheer impact as forced labor and diseases. However, it's always good to review multiple sources and perspectives to ensure a comprehensive understanding of the topic.