False. The proclamation of 1763 was a British law that prohibited American colonists from settling west of the Appalachian Mountains. While many colonists did ignore the proclamation and settle in these areas, it was not true that they largely ignored it. The proclamation led to tension and conflicts between the colonists and the British government.
True. American colonists largely ignored the Proclamation of 1763 and continued to settle west of the Appalachian Mountains. This was due to various reasons, including a desire for land and economic opportunities, as well as a general resentment towards British authority. This defiance of the proclamation eventually led to increasing tensions between the colonists and the British Crown.
