The various classes of immunoglobulins are differentiated on the basis of their ?antigen binding regions
affinity for antigens .
fixed segments .
variable regions .
shapes.
variable regions.
The various classes of immunoglobulins, also known as antibodies, are differentiated on the basis of their constant (fixed) segments and variable regions. The constant segments of the antibody determine its class, such as IgG, IgM, IgA, IgD, and IgE. These constant segments are responsible for mediating different effector functions of the antibodies within the immune system.
On the other hand, the variable regions of the antibody, located at the tips of the immunoglobulin molecule, are responsible for antigen binding. These variable regions contain antigen-binding sites, also known as antigen-binding regions or paratopes. The unique structure of the variable regions enables antibodies to recognize and bind to specific antigens, such as proteins, bacteria, viruses, and other foreign substances.
Therefore, it is correct to say that the classes of immunoglobulins are differentiated based on their constant segments, but it is the variable regions that confer specificity and affinity for antigens, allowing antibodies to recognize and bind to them.