Which effect did Spanish and Portuguese colonization have on South American Indians?

A.
Warfare, disease, and harsh treatment, including being forced to work in silver mines or sugar plantations, caused the deaths of many native people.

B.
South American Indians were assimilated into the European ruling class.

C.
Spanish and Portuguese colonization had less effect on South American Indians than it did on those native people living in Central America and the Caribbean.

D.
Many South American Indians emigrated to other parts of the Spanish or Portuguese empires.

A. Warfare, disease, and harsh treatment, including being forced to work in silver mines or sugar plantations, caused the deaths of many native people.