The key to understanding how DNA works is

a)to understand that each base only connects to another specific base.
b)to understand more about the sugar in each nucleotide.
c)to understand that it looks like a twisted ladder that spirals around.
d)to understand the role of the phosphate in each nucleotide.

The correct answer is c) to understand that DNA looks like a twisted ladder that spirals around. To understand how DNA works, it is essential to grasp its iconic structure known as the double helix. The double helix structure refers to two strands that are intertwined, resembling a spiral staircase or a twisted ladder. Each strand is made up of a long chain of nucleotides.

To explain the other options:
a) To understand that each base only connects to another specific base is also important in comprehending DNA's functioning. The four bases, adenine (A), thymine (T), cytosine (C), and guanine (G), form specific base pairs. Adenine always pairs with thymine (A-T), while cytosine always pairs with guanine (C-G). This base pairing is crucial in DNA replication and determining the genetic code.
b) Understanding more about the sugar in each nucleotide is also relevant as DNA's backbone is composed of alternating sugar and phosphate molecules. The sugar used in DNA is called deoxyribose, and it forms the core structure of each nucleotide.
d) Recognizing the role of the phosphate in each nucleotide is also necessary. Phosphates provide a negative charge and link the sugar molecules between consecutive nucleotides, forming the backbone of the DNA strand.

However, while these elements are all important components of DNA, the key to understanding how DNA works lies in comprehending its overall structure, specifically the double helix configuration.