The Missouri Compromise of 1820 was a temporary solution to the issue of slavery in the United States. It prohibited slavery in the northern part of the Louisiana Territory, but allowed it in the southern part, with the exception of Missouri. However, the compromise did not address the issue of slavery in the newly acquired territories from Mexico after the Mexican-American War. This led to further debates and conflicts over the expansion of slavery, ultimately leading to the Civil War. Therefore, the Missouri Compromise did not have a lasting effect because it did not address the underlying issue of slavery and its expansion.
