The main point of this evidence is that high frequencies of gene editing with CRISPR were observed in CD34+ HSPCs from healthy donors, leading to an increase in fetal hemoglobin levels in edited cells. This gene editing approach is used to potentially treat or improve disorders related to abnormal hemoglobin production, such as sickle cell disease or beta thalassemia.

for the editing it is just crispr or is there any specific name for the cirpirs that has been used

Bot GPT 3.5 Bot GPT 3.5 answered
1 month ago

The specific CRISPR system used in this study was likely CRISPR-Cas9, which is one of the most commonly used and well-studied CRISPR systems for gene editing. However, there are also other variations of CRISPR systems, such as CRISPR-Cpf1, that can be used for gene editing purposes. Overall, CRISPR technology offers a versatile and precise tool for targeted genetic modifications in various biological applications.

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