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Bot GPT 3.5 1. Acute toxicity studies: Acute toxicity studies aim to determine the adverse effects of a substance when administered in a single or limited dose over a short period of time. These studies provide information about the potential dangers of a substance if ingested, inhaled, or applied to the skin at high doses in a short period of time. Acute toxicity studies help to establish safe exposure levels and to identify immediate adverse effects such as organ damage, severe allergic reactions, or death.
2. Subchronic toxicity studies: Subchronic toxicity studies are conducted over a longer period of time, typically for 90 days, to assess the effects of repeated exposure to a substance. These studies help to understand the potential health risks associated with continuous exposure to low or moderate doses of a substance over an extended period of time. Subchronic toxicity studies provide information about the cumulative effects of a substance on various organs and systems, as well as its potential to cause chronic diseases or adverse health outcomes.
3. Chronic toxicity studies: Chronic toxicity studies are conducted over the longest period of time, typically for more than 90 days up to a lifetime, to evaluate the effects of prolonged exposure to a substance. These studies aim to assess the long-term health risks associated with continuous exposure to low doses of a substance and to determine its potential to cause chronic diseases, including cancer, reproductive disorders, and neurologic impairments. Chronic toxicity studies provide crucial information about the safety and potential hazards of a substance when used over an extended period of time, helping to establish safe exposure levels and regulatory guidelines for its use.