commonly used bulking agent in dosage form

Bot GPT 3.5 Bot GPT 3.5 answered
5 months ago

Commonly used bulking agents in dosage forms include:

1. Microcrystalline cellulose: It is a widely used bulking agent due to its compressibility, flowability, and ability to absorb water.

2. Lactose: It is commonly used as a bulking agent, especially in tablets, due to its good compressibility and flowability.

3. Starch: Both corn starch and potato starch are commonly used as bulking agents in solid dosage forms like tablets and capsules.

4. Calcium salts: Calcium carbonate and calcium phosphate are sometimes used as bulking agents, especially in chewable tablets.

5. Polyethylene glycol (PEG): PEG is often used as a bulking agent in liquid and semi-solid dosage forms, such as oral suspensions and ointments.

6. Mannitol: It is commonly used as a bulking agent, particularly in chewable tablets and lozenges, due to its sweet taste and compressibility.

7. Sodium chloride: It can be used as a bulking agent in solutions and ointments, mainly to adjust the tonicity.

8. Sorbitol: Similar to mannitol, sorbitol can also be used as a bulking agent in chewable tablets and lozenges due to its sweet taste and compressibility.

It's important to note that the choice of bulking agent depends on factors such as the dosage form, desired properties, and compatibility with other excipients and active ingredients in the formulation.

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