To translate figure PQRS 6 units down and 2 units to the right, we need to subtract 6 from the y-coordinate of each vertex and add 2 to the x-coordinate of each vertex.
The coordinates of P are (4, 6).
When we subtract 6 from the y-coordinate and add 2 to the x-coordinate, we get (4 + 2, 6 - 6) = (6, 0).
Therefore, the coordinates of P' are (6, 0).
The correct response is (6, 0).