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Sign: A sign is an objective indication of a medical condition that can be observed by a doctor or other healthcare professional. Examples of signs include a fever, rash, or elevated blood pressure.
Symptom: A symptom is a subjective indication of a medical condition that is reported by the patient. Examples of symptoms include headache, fatigue, or nausea.
Syndrome: A syndrome is a collection of signs and symptoms that occur together and characterize a particular medical condition. Examples of syndromes include Down syndrome, Marfan syndrome, and Turner syndrome.