Refer to the family pedigree shown here. In generation 1 one parent is affected by the gene mutation and one parent isnt. I generation 2 all three children are affected by the gene mutation. What can you conclude about this gene mutation?
The gene is dominant and the one parent is homozygous for the gene.
No pedigree shown. Cannot copy and paste here.
Unclear, but it it seems like the gene mutation is dominant. By affected, I assume that you means that it shows up in the phenotype. The chances of all three children inheriting the mutation is 1/2^3 = 1/2*1/2*1/2 = 1/8.
Based on the information provided, we can conclude that the gene mutation is likely dominant.
In generation 1, one parent is affected by the gene mutation and one parent is not. This indicates that the gene mutation is present in one of the parents, who is affected by it, while the other parent does not have the mutation.
In generation 2, all three children are affected by the gene mutation. This suggests that the gene mutation has been passed down from the affected parent to all their children, resulting in all of them being affected by the mutation.
If the gene mutation was recessive, it would require both parents to carry the mutation in order for it to be expressed in the offspring. However, since only one parent is affected in this case, it indicates that the gene mutation is dominant.
To analyze the conclusion about this gene mutation based on the family pedigree, we need to understand the inheritance patterns of the gene mutation. The pedigree can provide insights into whether the gene mutation is dominant or recessive and how it is passed down from generation to generation.
Based on the information provided, let's break down the generations and assess the conclusions:
Generation 1: One parent is affected, and one parent is unaffected.
- This implies that the gene mutation might be inherited in one of three ways: autosomal dominant, autosomal recessive, or X-linked dominant.
Generation 2: All three children are affected.
- If the gene mutation were autosomal dominant, we would expect that at least one of the parents would also exhibit the mutation. Since only one parent is affected, it suggests that the mutation is likely not autosomal dominant.
- If the gene mutation were autosomal recessive, both parents would be carriers since none of them show the mutation. In this case, there would be a 25% chance for each child to be affected. However, since all three children are affected, it indicates that the mutation is most likely not autosomal recessive.
- If the gene mutation were X-linked dominant, we would expect to see the mutation in each generation, affecting males and females differently. However, based on the information provided, it is not possible to determine if the mutation is X-linked dominant.
Given the available information, we can conclude that the gene mutation is most likely autosomal recessive. This conclusion is based on the fact that both parents do not show the mutation, but all three children are affected. However, further analysis and information would be required to confirm this conclusion definitively.