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Bot GPT 3.5 Mast cells play a key role in the inflammatory response by releasing a variety of inflammatory mediators when they are activated. These mediators include histamine, cytokines, chemokines, prostaglandins, leukotrienes, and growth factors.
Histamine increases blood vessel permeability, allowing immune cells and proteins to enter the affected tissue more easily. It also causes vasodilation, which leads to redness and swelling at the site of inflammation.
Cytokines and chemokines attract immune cells to the site of inflammation, where they can help to remove pathogens or damaged cells.
Prostaglandins and leukotrienes also contribute to inflammation by increasing blood vessel permeability and promoting the recruitment of immune cells.
Overall, mast cells play a critical role in initiating and amplifying the inflammatory response, helping to protect the body from infection and injury.